7-Keto is a metabolite (modified molecule) of the hormone precursor DHEA. It promotes weight loss by boosting metabolism safely, without stimulants. Scientists discovered that 7-Keto is a potent activator of 3 important thermogenic enzymes, which help the body convert stored fat to energy. Supplementing with 7-Keto helps accelerate weight loss so that you can achieve your goal weight faster. 7-Keto is the trade name for the compound 3-acetyl-7-oxodehydroepiandrosterone or 7-oxo DHEA, which is a substance, found naturally in the human body. It is metabolized from the hormone precursor DHEA, and like DHEA, declines with age. Dr. Henry Lardy, Vilas Professor Emeritus of the Institute for Enzyme Research at the University of Wisconsin in Madison, led the search for more specific and active metabolites of DHEA that do not have the potential unwanted side effects of DHEA which could convert to testosterone or estrogen. Their search discovered the advantages of the 7-oxo-DHEA metabolite as an effective weight loss ingredient. Many have advocated supplementing with DHEA as researchers noted that as DHEA levels decline with age:
• The incidence of obesity increases.
• Reproductive function decreases.
• Basal metabolic rate decreases.
• Immune function decreases.
• Age related skin changes increase.
We experience a 40% reduction in DHEA levels between ages 20 and 40, and it then declines even further to negligible amounts by 70+ years of age. Supplementing with 7-Keto is simply putting back what aging has taken away. Unlike DHEA, 7-Keto does not convert to androgens and estrogens.
Thermogenic enzyme activation
Dr. Lardy and his team discovered that 7-Keto DHEA was 2.5 times more active at stimulating thermogenic enzymes glycerol-3- phosphate- dehydrogenase, Malic Enzyme and fatty acyl CoA oxidase. All three of these enzyme activations promote the utilization of fat stores for energy and heat production.
Two independently conducted double-blind, placebo-controlled clinical trials support the effectiveness of 7-Keto for weight loss. The results of the study suggest that 7-oxo-DHEA combined with moderate exercise and a reduced calorie diet significantly reduces body weight and body fat compared with exercise and a reduced-calorie diet alone. Both studies have been published in international peer reviewed journals.
- Clinically proven
- Gives the body what it naturally produces
- 3x times more weight loss than diet and exercise alone
- Increases metabolism by up to 5.4%
- Activates 3 thermogenic enzymes
- Promotes stimulant free weight loss
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